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These findings are summarized in a Cochrane review (238) including one study with high-dose Zn intake [(305), 10 mg/day] and 4 studies with low (currently recommended) dose were included (63, 64, 306, 307)

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As a nitrogen donor, it contributes to the synthesis of other non-essential amino acids, including the purines and pyrimidines, and is therefore essential for the proliferation of most cells (29)